This book offers a philosophy for error-prone humans trying to understand messy systems in the real world.

Over the past several years a cascade of corporate scandals have erupted. Savings and provisions for retirement have shrunk drastically. Jobs have been lost. One of the world's largest and best-known accounting firms is gone. Ordinary people have been hurt and they have lost confidence in business leaders. The on-going public debate over business ethics and corporate reform points to one common conclusion: Things cannot be corrected by simply adding more laws and new rules. The solution will come from high (...) moral leadership. The Heart of A Business Ethic is based on the Hansen-Wessner Lectureship Series established by the ServiceMaster Foundation to consider the source of moral authority and ethical behavior in business. The eight lectures in this series were presented at major universities in the U.S. and Britain, and brought together some of the most distinguished business experts of our time. What they have to say is important for business teachers and students, and business leaders at every level. The scandals at Enron, Tyco and others have generated many books on business ethics, but none offer the expertise or breadth of thinking that this volume does. The Heart of A Business Ethic is useful to professors, students, and practitioners who not only want to understand what has happened, but who also want to think through the basis for a new standard of morality in business. (shrink)

Lying in an area bounded by the Wabash, Ohio, and Mississippi rivers, the Southern Illinois country is rich in history, folklore, scenery, and natural resources. At about the latitude of southern Virginia, and extending from the flat prairie farmland of central Illinois to the rugged "Illinois Ozarks,” the area is the natural terminal boundary for hundreds of plant species reaching out to all points of the compass. It is also the oldest and most sparsely populated part of Illinois, a region (...) of small towns and independent people, typical of the vast heartland of the U.S.A. Surveying the area in words and pictures the authors sensitively and appreciatively portray the region’s special qualities. An uncommon portrayal of American life in a distinctive region, the book provides a memorable journey both in time and place. (shrink)

Willard van Orman Quine once said that he had a preference for a desert ontology. This was in an earlier day when concerns with logical structure and ontological simplicity reigned supreme. Ontological genocide was practiced upon whole classes of upper-level or ‘derivative’ entities in the name of elegance, and we were secure in the belief that one strayed irremediably into the realm of conceptual confusion and possible error the further one got from ontic fundamentalism. In those days, one paid more (...) attention to generic worries about possible errors than to actual errors derived from distancing oneself too far from the nitty-gritty details of actual theory, actual inferences from actual data, the actual conditions under which we posited and detected entities, calibrated and ‘burned in’ instruments, identified and rejected artifacts, debugged programs and procedures, explained the mechanisms behind regularities, judged correlations to be spurious, and in general, to the real complexities and richness of actual scientific practice. (shrink)

The emergence of Big Data has added a new aspect to conceptualizing the use of digital technologies in the delivery of public services and for realizing digital governance. This article explores, via the ‘value-chain’ approach, the evolution of digital governance research, and aligns it with current developments associated with data analytics, often referred to as ‘Big Data’. In many ways, the current discourse around Big Data reiterates and repeats established commentaries within the eGovernment research community. This body of knowledge provides (...) an opportunity to reflect on the ‘promise’ of Big Data, both in relation to service delivery and policy formulation. This includes, issues associated with the quality and reliability of data, from mixing public and private sector data, issues associated with the ownership of raw and manipulated data, and ethical issues concerning surveillance and privacy. These insights and the issues raised help assess the value of Big Data in government and smart city environments. (shrink)

Two essays on utilitarianism, written from opposite points of view, by J. J. C. Smart and Bernard Williams. In the first part of the book Professor Smart advocates a modern and sophisticated version of classical utilitarianism; he tries to formulate a consistent and persuasive elaboration of the doctrine that the rightness and wrongness of actions is determined solely by their consequences, and in particular their consequences for the sum total of human happiness. In Part II Bernard Williams offers a sustained (...) and vigorous critique of utilitarian assumptions, arguments and ideals. He finds inadequate the theory of action implied by utilitarianism, and he argues that utilitarianism fails to engage at a serious level with the real problems of moral and political philosophy, and fails to make sense of notions such as integrity, or even human happiness itself. This book should be of interest to welfare economists, political scientists and decision-theorists. (shrink)

Most philosophical accounts of emergence are incompatible with reduction. Most scientists regard a system property as emergent relative to properties of its parts if it depends upon their mode of organization-a view consistent with reduction. Emergence is a failure of aggregativity, in which ``the whole is nothing more than the sum of its parts''. Aggregativity requires four conditions, giving powerful tools for analyzing modes of organization. Differently met for different decompositions of the system, and in different degrees, the structural conditions (...) can provide evaluation criteria for choosing decompositions, ``natural kinds'', and detecting functional localization fallacies, approximations, and various biases of vulgar reductionisms. This analysis of emergence and use of these conditions as heuristics is consistent with a broader reductionistic methodology. (shrink)

This article explores the emergence of standards and regulation associated with the provision of Closed Circuit Television (CCTV) surveillance systems in the United Kingdom. It argues that despite the intrusive and controlling nature of CCTV technology there is limited formal intervention in the form of legislation, governing its introduction and use. Instead government has sought to influence the regulation of the technology indirectly through its ability to shape and govern policy networks in the policy arena. In doing so, it is (...) argued here, that government remains the dominant actor in the policy process. (shrink)

It would surely have been better to entitle this work ‘Reflexions on ethical theories’, for it cannot in any true sense of the word be called a study, a scientific study which entails detailed analysis and positive criticism. In fact Professor Mackinnon presents us with a series of considerations, highly personal and at times indeed penetrating and instructive, on the moral theories of certain British and continental philosophers—of the 19th century utilitarians ; of Kant, Hegel and their followers; of the (...) theologianphilosopher bishop of Durham, Joseph Butler; of Russell, Moore and others. The impression left on one after a careful perusal of the work is that it is no more than an agglomeration of ‘mights’ and ‘perhaps’, never a clear–cut judgment. The chief general defect of the book and the cause of much obscurity is certainly this: the absence of any welldefined distinction between exposé and critique. As often as not one does not know what the opinion of the author is as distinct from his interpretation of the authors he is studying. This defect would seem to be characteristic of a great part of the ethical writing produced by the Scottish and British schools, when they do not reduce ethical theory to anything better than semasiology, to a study of ethical language or linguistic usage. Prof. Mackinnon has certainly not freed himself from the ‘present confused state of moral philosophy in this country’, which he so rightly condemns. I had thought that all philosophers, of whatever ilk, were agreed that ethical science or moral philosophy was nothing more than the study of the human being on its way towards completeness in human being, from an initial embryonic stage, as it were, to the full flowering of human perfection, manifested in perfect human being and perfect human life—a journey or precess directed and controlled by the human subject itself, fully conscious of the end to be achieved and conscious too of the steps or means towards it. I would have thought too that if we are to set up moral science as distinct from mere semasiology, or from psychology, biology, zoology or botany, then all were agreed that we have to do with the domain of free activity, of voluntary conscious activity, which obviously brings with it the order of responsibility and willed subjection to a given objective order of things, that is, of human nature itself and human perfection. I would have taken for granted too that one could study all this field of the free development of the human being towards its ultimate perfection either with a view to the acquisition of knowledge and nothing more, or precisely with a view to being in a position to direct oneself and others towards that fullness of being. That would give us two distinct modes of moral or ethical theory, the speculative or theoretical and the practical and normative, the resolutive and the compositive. I am not so sure that Professor Mackinnon is ready to admit these presupposita. He speaks of the ‘curious and almost silly claim that we are free’, and at the same time he can write about the ‘frankly metaphysical reality of freedom’, or its ‘near–metaphysical reality’. This, in the language of the author, is just another way of proclaiming that human freedom is no more than a myth, lacking all substance and reality. Moral science as distinct from all other sciences, one would think, presupposes that the moral subject be conscious of itself and its activity, that is, that it fully and clearly know that its life and its activity is its own. It must be master of its own actions, and in that sense truly master of its own destiny. Then and only then are we in the order of moral activity. However, we are warned by Professor Mackinnon that “to know that an action is mine is a very strange sort of knowledge, quite different from knowing that an apple or a book is mine: to use the word ‘know’ in such a context is a venture fraught with intellectual peril”. I sincerely think it would have been better had the author denied straight out the possibility, not just of metaphysics, but of ethical theory tout court; for he denies often enough the existence of the moral subject, namely, man freely and deliberately ordaining himself towards human consummation. Had he done that at the outset he would have been spared the trouble of writing his book. All in all, one gets the distinct impression that the author is just not sure of his ground and has no really sound criterion whereby to judge of various ethical theories. In fact the book ends with a big question–mark: ‘If we speak and write thus, do we speak and write sound and fury signifying nothing?’. Reluctantly I am constrained to answer in the affirmative. And I should like to add, so as not to appear completely destructive, but in some way constructive: if, instead of dismissing Aristotle and his followers, ancient and modern, as mere ‘intuitionists’, Professor Mackinnon would only study them seriously he would first of all find out how unjustified is his condemnation of them and then, I venture to suggest, he would acquire a light to guide him surely through the maze of ethical theory with which he grapples aimlessly and would thus be enabled to extricate himself from ‘the present confused state of moral philosophy’ in Britain. (shrink)

This paper attempts to provide a conceptual underpinning for codes of ethics in business and the professions. Rule-utilitarianism is a theory of ethics which I believe can successfully do this. Business persons and professionals, hopefully, will be able to develop codes of ethics in a manner consistent with a well-formulated general ethical theory. This will help enable codes of ethics to be a bridge between general ethical theory and specific ethical decisions made in business and the professions.

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

This book introduces the work of an important medieval Islamic philosopher who is little known outside the Persian world. Afdal al-Din Kashani was a contemporary of a number of important Muslim thinkers, including Averroes and Ibn al-Arabi. Kashani did not write for advanced students of philosophy but rather for beginners. In the main body of his work, he offers especially clear and insightful expositions of various philosophical positions, making him an invaluable resource for those who would like to learn the (...) basic principles and arguments of this philosophical tradition but do not have a strong background in philosophy. Here, Chittick uses Kashani and his work to introduce the basic issues and arguments of Islamic philosophy to modern readers. (shrink)

Benedikt Stattler was born on January 30, 1728 in Kötzting in Bavaria. In 1745 he entered the Society of Jesus, to which he remained loyal in spirit and in deed until his death, in spite of its suppression in 1773 by Clement XIV From 1760 until 1781 he taught philosophy and theology in Staubing, Solothurn, Innsbruck and Ingolstadt, where the famous J. M. Sailer, Bishop of Regensburg, was his pupil. He died in Munich in 1797. Stattler, then, lived and worked (...) at the very height of the so-called Aufklarungszeit, a fact which had the deepest repercussions on his whole career. He was a zealous man and truly apostolic. Perhaps, if anything he was over-zealous and was in fact carried much too far in his spirit of accommodation and flexibility when faced with the rationalist enemies of the Church and Christianity. He was filled with the idea that they should be met on their own ground in order to win them for the Church. And in order to do that he decided that he must break with tradition. Modern modes of thinking must be used if there is to be even the possibility of discussion with present-day thinkers, was his principle. Accordingly he brushed aside Aristotle, St. Thomas and all the Scholastics and made his own the philosophy of Christian Wolff. For him that was the only way of preserving the Christian and Catholic faith and of safeguarding Christian morality, the Christian way of life. Filled with that idea he wrote indefatigably. Many of his works, however, very early fell foul of the Roman authorities and were put on the Index of forbidden books. And in fact, as Dr. Scholz rightly points out over and over again, Stattler became a victim of the Aufklärung which he sought to Christianize and he himself became a rationalist and, in morals, and out-and-out subjectivist. (shrink)

Since children are considered incapable ofgiving informed consent to participate inresearch, regulations require that bothparental permission and the assent of thepotential child subject be obtained. Assent andpermission are uniquely bound together, eachserving a different purpose. Parentalpermission protects the child from assumingunreasonable risks. Assent demonstrates respectfor the child and his developing autonomy. Inorder to give meaningful assent, the child mustunderstand that procedures will be performed,voluntarily choose to undergo the procedures,and communicate this choice. Understanding theelements of informed consent has been theparadigm for (...) assessing capacity to give assent.This method leaves the youngest, leastcognitively mature children vulnerable towaiver of assent and forced researchparticipation. Voluntariness can also becompromised by the influence of authorityfigures who can exert undue influence andcoerce children to participate in research. This paper discusses factors that may influencethe decision to give assent/permission,potential parent-child conflict in theassent/permission process and how it isresolved, and potential parental undueinfluence on research participation. Theseissues are illustrated with quotations drawnfrom a larger qualitative study of parentalpermission and child assent (data notpresented). We suggest a developmentalapproach, viewing assent as a continuum rangingfrom mere affirmation in the youngest childrento the equivalent of the informed consentprocess in the mature adolescent. (shrink)

A recent legal case involving an ambiguous diagnosis in a woman with a severe disorder of consciousness raises pressing questions about treatment withdrawal in a time when much of what experts know about disorders of consciousness is undergoing revision and refinement. How much should diagnostic certainty about consciousness matter? For the judge who refused to allow withdrawal of artificial nutrition and hydration, it was dispositive. Rather than relying on substituted judgment or best interests to determine treatment decisions, he ruled that (...) withdrawal was categorically prohibited, even as he concluded that Hannah Capes was more likely than not in a permanent vegetative state. In many jurisdictions, his decision would likely be consistent with existing law. Evolving technological advances have demonstrated that biologically distinct diagnoses incorporated into state laws may be difficult to establish even under ideal conditions. We offer the Capes case for purposes of examining the consequences of enshrined legal distinctions between permanent vegetative state and other severe disorders of consciousness. Insistence on proof of the permanent absence of consciousness before treatment withdrawal is allowed fails to respect the rights of persons with disorders of consciousness. Even the well-established rights to treatment withdrawal for those in a permanent vegetative state may be in jeopardy if reform is not undertaken. (shrink)

Arne Naess and Paul Taylor are two of the most forceful proponents of the principle of species equality. Problematically, both, when adjudicating conflict of interest cases, resort to employing explicit or implicit species-ranking arguments. I examine how Lawrence Johnson’s critical, species-ranking approach helpfully avoids the normative inconsistencies of “biospherical egalitarianism.” Many assume species-ranking schemes are rooted in arrogant, ontological claims about human, primate, or mammalian superiority. Species-ranking, I believe, is best viewed as a justified articulation of moral priorities in response (...) to individuals’ or entities’ relative ranges of vulnerability and need, rooted in their relative ranges of capacities and interests. (shrink)

The author of this little book makes no claim to being a philosopher, and is fully conscious of the very obvious limits of his writing ability. He is fully aware, too, of the nebulousness of his task, the task, namely, which he has taken upon himself of discussing what he calls universal religion on the basis of the Bible, the Talmud and the history of the Jewish people. Overcoming, however, his reluctance to divulge his ideas in writing because he feels (...) intuitively that he can transcend all his human frailty, he sets about presenting us with a philosophy of entire existence, as he himself puts it. A formidable task indeed. He would be grievously hurt, he tells us, were we to label his effort as theology. And still we are within our rights to ask: what else but theology could or should be the rational penetration of what God has spoken to men? In fact, the finished product turns out to be neither philosophy nor theology, but rather a series of pious, at times even pseudo-mystical reflections on God’s revelation as found in the Old Testament and as interpreted down the centuries in the various Jewish traditions. The serious philosopher or earnest theologian or the historian of religions will find nothing here. (shrink)

Cognitive agents, whether human or computer, that engage in natural-language discourse and that have beliefs about the beliefs of other cognitive agents must be able to represent objects the way they believe them to be and the way they believe others believe them to be. They must be able to represent other cognitive agents both as objects of beliefs and as agents of beliefs. They must be able to represent their own beliefs, and they must be able to represent beliefs (...) as objects of beliefs. These requirements raise questions about the number of tokens of the belief representation language needed to represent believers and propositions in their normal roles and in their roles as objects of beliefs. In this paper, we explicate the relations among nodes, mental tokens, concepts, actual objects, concepts in the belief spaces of an agent and the agent's model of other agents, concepts of other cognitive agents, and propositions. We extend, deepen, and clarify our theory of intensional knowledge representation for natural-language processing, as presented in previous papers and in light of objections raised by others. The essential claim is that tokens in a knowledge-representation system represent only intensions and not extensions. We are pursuing this investigation by building CASSIE, a computer model of a cognitive agent and, to the extent she works, a cognitive agent herself. CASSIE's mind is implemented in the SNePS knowledge-representation and reasoning system. (shrink)

The term “effective,” on its own, is honorific but vague. Interventions against serious mental illness may be “effective” at goals as diverse as reducing “apparent sadness” or providing housing. Underexamined use of “effective” and other success terms often obfuscates differences and incompatibilities in interventions, degrees of effectiveness, key omissions in effectiveness standards, and values involved in determining what counts as “effective.” Yet vague use of such success terms is common in the research, clinical, and policy realms, with consequences that negatively (...) affect the care offered to individuals experiencing serious mental illness. A pragmatist-oriented solution to these problems suggests that when people use success terms, they need to explain and defend the goals and supporting values embedded in the terms, asking and answering the questions, “Effective at what? For whom? How effective? And why that goal?” Practical and epistemic standards for effectiveness will likely remain plural for good reasons, but each standard should be well explained and well justified. (shrink)

Women do most of the parenting. To provide a stable and healthier setting for children they must sublimate their own interests and feelings, which puts greater pressures on women to communicate needs clearly or to be deceptive when the occasion demands. The likely advantage in communication skills and self-control may ameliorate the impact of disorders like ADHD where the most serious deficit is in self-inhibition. This would account for the strikingly uneven male to female sex ratio of 2:1 (in epidemiological (...) samples) to 10:1 (in clinical settings), the higher threshold for females, and the sex difference in the pattern of associated mental disorders. (shrink)

This book examines the origins and subsequent evolution of multicellularity. The transition from unicellular to multicellular life was one of a few major events in the history of life that created new opportunities for more complex biological systems to evolve.

Through discourse with international groups of physicians, we conducted a cross-cultural analysis of the types of ethical dilemmas physicians face. Qualitative analysis was used to categorise the dilemmas into seven themes, which we compared among the physicians by country of practice. These themes were a-theoretically-driven and grounded heavily within the text. We then subjected the dilemmas to an analysis of moral intensity, which represents an important theoretical perspective of ethical decision making. These constructs represent salient determinants of ethical behaviour and (...) our cross-cultural sample afforded us the opportunity to consider both the pragmatic aspects of culture, as they are perceived by physicians, as well as the theory-driven concept of moral intensity. By examining both culture and moral intensity, we hope to better elucidate the complexities of ethical decision-making determinants among physicians in their daily practice. Doing so may potentially have practical implications for ethics training of medical students and foreign physicians. (shrink)

We comment that covariances between brain divisions may be constraining or facilitating, depending on what is being selected, and that modern quantitative genetic methods provide the tools to discover and manipulate the genetic networks that give rise to the covariances described in the target article.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Parts I through III of this paper will examine several, increasingly comprehensive forms of aggregation, ranging from insurance reimbursement “lock-in” programs to PDMPs to completely unified electronic medical records. Each part will advocate for the adoption of these aggregation systems and provide suggestions for effective implementation in the fight against opioid misuse. All PDMPs are not made equal, however, and Part II will, therefore, focus on several elements — mandating prescriber usage, streamlining the user interface, ensuring timely data uploads, creating (...) a national data repository, mitigating privacy concerns, and training doctors on how to respond to perceived doctor-shopping — that can make these systems more effective. In each part, we will also discuss the privacy concerns of aggregating data, ranging from minimal to significant, and highlight the unique role of stigma in motivating these concerns. In Part IV, we will conclude by suggesting remedial steps to offset this loss of privacy and to combat the stigma around SUDs and mental health disorders in general. (shrink)

The effect of oxytocin on cognitive bias was investigated in rats in a modified conditioned place preference (CPP) paradigm. Fifteen male rats were trained to discriminate between two different cue combinations, one paired with palatable foods (reward training), and the other paired with unpalatable food (aversive training). Next, their reactions to two ambiguous cue combinations were evaluated and their latency to contact the goal pot recorded. Rats were injected with either oxytocin (OT) or saline with the prediction that rats administered (...) oxytocin would display a shorter average latency to approach on ambiguous trials. There was no significant difference between latencies to approach on ambiguous trials compared to reward trials, but the rats were significantly slower on the aversive compared to the ambiguous conditions. Oxytocin did not affect approach time; however, it was unclear, after follow-up testing, whether the OT doses tested were sufficient to produce the desired effects on cognitive bias. Future research should consider this possibility. (shrink)